His origin could be that he was first introduced to comics by a family member or friend. This initial exposure led to a lifelong love affair with comic books. He then dedicated his life to collecting, reading, and sharing his knowledge about comics, thus becoming the 'comic book guy'.
Sure. Bruce Banner got caught in gamma radiation during an experiment, turning into the Hulk when angry.
Sure. Wade Wilson had cancer and joined an experiment to cure it. The experiment gave him powers like super healing and made him Deadpool.
If 'it' is a story element, like a magical object in a fairy tale. The origin story could be that it was created by a powerful wizard long ago for a specific purpose, and as the story unfolds, its origin might be gradually revealed through the plot and characters' discoveries.
Sure. 7 - Eleven started in Texas in 1927 as a store mainly selling ice. It got its name from its operating hours of 7 am - 11 pm.
Carol was involved with Kree stuff. An accident with their tech gave her powers. Simple as that, but it's a really cool and crazy origin.
Sure. Black Adam was a slave in Kahndaq. He got powers from Shazam but went bad.
Sure. Usually, it's the idea of an artist or writer who was fascinated by black cats. They thought a black cat could make an interesting character in a comic. So they created a story around it.
The Dutton origin story likely involves the family's start, perhaps in a particular region. It's about their early days and how they came to be.
The 'earth origin story' in brief is that after the Big Bang, there was a nebula. The nebula's material condensed due to gravity, and the Earth was one of the bodies formed from that condensed matter.
The 'roadhog origin story' probably has to do with his rise in a desolate world. He may have been driven to his current state by the need to survive.