I think Hinata would be an interesting character to interact with Naruto as a girl. Hinata has always had a bit of a crush on Naruto, and now that he's a girl, it could lead to a very different kind of relationship. They could become closer friends or even something more. Also, Tsunade. Tsunade could be a great mentor for Naruto in her new female form, teaching her things about being a female ninja that she didn't know before.
Sasuke would be really interesting. His relationship with Naruto was always complex, and if Naruto is a girl, it could add a new level of tension or even a different kind of friendship/rivalry. Sakura too. She might have a whole new perspective on Naruto as a girl, and they could form a stronger bond as female comrades. And Kakashi, his reaction to Naruto's transformation could be quite humorous and also a source of guidance for Naruto in this new situation.
Definitely Jiraiya. His reaction to Naruto being turned into a girl would be priceless. He might be a bit flustered at first but then could see it as an opportunity to train Naruto in a different way. Another interesting character would be Ino. Ino could help Naruto with things like fashion or how to act more 'girly' if Naruto is interested in that. And Rock Lee. Lee's pure - hearted nature would make his interactions with Naruto as a girl really fun to read about, as he would likely treat her the same as before but also be a bit more protective perhaps.
Sasuke would definitely be one of the main characters to interact with Naruto. Their relationship has always been complex, and with Naruto as a girl, it could become even more so. Sakura would also interact a lot. She might be both jealous and intrigued by Naruto's new form. Kakashi too, as Naruto's mentor, would have to adjust to this change and guide 'her' in a different way perhaps.
Iron Man is another candidate. Tony Stark's technology and Naruto's ninja techniques could be a great contrast. They could learn from each other. Stark might be interested in Naruto's chakra - based powers and try to replicate them in some way, while Naruto could be amazed by Stark's high - tech gadgets.
Tsunade would definitely be one. As the most renowned medical ninja in the village, she could either be Naruto's mentor or a colleague. They could exchange medical knowledge and experiences.
Naruto might interact with Eostia's warriors. They could train together, Naruto showing them his ninja combat skills and them teaching him about Eostia - style combat. There could also be some mysterious characters in Eostia, like an old hermit who has some knowledge about Naruto's sudden appearance in their world and could guide him on his journey in Eostia.
Naruto and the lead character from Warrock would be really interesting. Naruto with his never - give - up attitude and the Warrock lead, who is probably used to a different set of rules and technology. Their clash of personalities and ways of doing things could create some great story moments.
Definitely the Teen Titans. Robin would be interested in Naruto's strategic mind and combat skills. Starfire might be fascinated by Naruto's unique culture. Beast Boy and Naruto could bond over their fun - loving natures. And Cyborg would be intrigued by Naruto's chakra - based abilities compared to his technological ones.
Ruby Rose for sure. She's the main character in Remnant and Naruto would likely be drawn to her energy and determination. He could also interact with Weiss Schnee. Naruto might be interested in her family's power and wealth, and Weiss could be curious about Naruto's strange abilities. Another one could be Blake Belladonna. Given her past and her more reserved nature, Naruto might try to befriend her and help her open up more.
He could interact with Mei Terumi, the Mizukage. She might be initially cautious of Naruto but then see his potential and work with him. Also, Chojuro, as he is one of the important ninjas in Kiri. They could train together or go on missions side by side.
Well, Kakashi could play an important role. Since he was Naruto's mentor, he would be very curious about Naruto's sudden change to a nobody. He might secretly investigate what caused this. Shikamaru could also interact with Naruto. Shikamaru is smart and observant. He might notice some small details about Naruto that others miss, and try to figure out the mystery behind Naruto becoming a nobody. Also, Rock Lee could be in the story. Lee might see Naruto as a new opportunity to spread his 'youth' spirit, not knowing Naruto's past.
Well, R2 - D2 and C - 3PO could be characters that Naruto interacts with. R2 - D2 could help Naruto understand some of the technology in the Star Wars universe with his beeps and whistles. C - 3PO could translate things for Naruto if he needs to communicate with different species. And then there's Finn. Finn could team up with Naruto, both being characters who are sort of outsiders in their respective worlds. They could fight side by side against the common enemies of the dark side forces in the Star Wars universe.