The gods could potentially be antagonists. If the pregnancy goes against some divine law or prophecy, they might try to interfere. For instance, Zeus could see it as a threat to the order of things and send his minions to cause trouble for Percy and Bianca.
A group of rogue demigods could also be antagonists. These demigods might be jealous of Percy's status and Bianca's unique abilities. They could form a sort of anti - hero group that tries to undermine Percy and Bianca's quests and cause trouble for them. For example, they might steal important items that Percy and Bianca need for their mission.
It could be the entities that thrive on the disorder in the chaos. They might see Percy and Bianca as threats to their way of life and try to stop them from achieving whatever goal they have in the chaos.
The main antagonists could be some of the other gods who are jealous of Aphrodite's special situation with Percy. For example, Hera might not like the idea of Aphrodite having a child with a demigod, as it goes against the normal order of things in the godly realm.
The old enemies of Percy and Annabeth like the Titans or some of the more vengeful monsters could be the main antagonists. They might see the unborn child as a threat or an opportunity to get back at Percy and Annabeth.
The other gods who oppose the relationship between Percy and the goddess could be antagonists. They might see it as a disruption of the natural order or a threat to their power. For example, if the goddess is from a certain pantheon and her pregnancy by a mortal like Percy goes against their rules, those traditionalist gods would be against it.
One antagonist could be an old enemy of Levi's who resurfaces during Petra's pregnancy. This enemy wants to take revenge on Levi by targeting what he holds dear, which is now Petra and their unborn baby. They might set up traps or create dangerous situations for the couple. Additionally, there could be some traditionalists in their military organization who don't approve of soldiers having a family and try to make their lives miserable during the pregnancy.
Frieza or his remnants could be antagonists. They might see the unborn child as a potential threat in the future, especially if it has strong Saiyan powers. So they could plan to attack Bulma to prevent the birth.
The Capitol could still be the main antagonists. They might see Katniss's pregnancy as a threat, either because they fear the child could grow up to be a symbol of resistance like Katniss or just because they want to maintain control over her. They could try to harm her or the baby in some way.
The other vampires in Mystic Falls who are against the idea of a hybrid - vampire baby could be antagonists. They might see it as a threat to their way of life.
Other tributes or survivors who are jealous or resentful could also be antagonists. They might not like the idea of Katniss and Finnick having a family when they have lost so much themselves. This could lead to conflict and attempts to harm them or the baby.