Maybe he lost his way and the map is his guide to find the right direction.
It could be that the map leads to a hidden treasure and he's in a rush to get there first. Or perhaps it holds some important information he desperately needs.
Maybe the man has some special mission or is trying to protect the girl.
Maybe it's because the idea didn't catch the interest of producers or there weren't enough resources to make it.
It could be that he's in a hurry to get somewhere important and is panicking. Or perhaps he saw something unexpected that frightened him.
Maybe it's trying to escape from something or chasing after something it wants.
The cartoon man with tools running might be in a race or competition where having the tools is a requirement. Or he could have just discovered an emergency and is dashing off to solve it with the tools at hand.
There could be various reasons. It might be a form of satire, aiming to draw attention to a particular issue. Or it could simply be an unconventional creative choice by the artist to shock or surprise the audience.
The cartoon man and woman might be running because they are late for an important event. It could also be that they are just having fun and being playful.
Maybe he's late for a flight and has to catch it. Or he could be running away from something and the suitcase has his important stuff.
Maybe he saw some great deals and didn't want to miss out.
Maybe he's in a hurry to catch something or someone.