It might be related to her own past traumas in Konoha. She could have faced discrimination or unfair treatment due to her Uzumaki heritage, and she doesn't want Naruto to experience the same. So she leaves with him to start a new life in a more accepting place.
One possible reason could be to protect Naruto from the hidden threats in Konoha. Maybe she discovers some dark secrets or plots within the village that she believes will endanger Naruto, so she decides to take him away.
One possible reason could be for Naruto's safety. Maybe she has to go on a dangerous mission and believes Konoha is the safest place for him. Another reason might be that she is forced by some powerful enemies who threaten Naruto's life if she doesn't leave him in Konoha.
One possible reason could be a mission. In many Naruto - related stories, missions often take characters away from their families. Naruto might have received a highly important and dangerous mission that requires him to be away from Kushina for a long time.
One possible reason could be for his safety. Konoha is a well - protected village with many skilled ninja. She might believe that leaving him there would ensure he has the best chance at survival and growth as a ninja. Also, she may have some mission or obligation that forces her to leave him behind, perhaps something related to the greater good of the village or the ninja world in general.
The relationship between Konoha and the Uzumaki clan might be further strained. With Kushina leaving, Konoha would lose an important link to the Uzumaki. And other Uzumaki members might see this as a sign that Konoha is not a safe place for them.
In a 'naruto and kushina leaves konoha fanfic', perhaps they leave due to a threat to Naruto's safety that the village can't fully protect against. Maybe some secret organization is after him and they feel they have no choice but to go into hiding outside Konoha.
One possible reason could be that Kushina has a very strong and intimidating personality. In the Naruto universe, she was known to be a tough kunoichi. Naruto, who might be used to more gentle or reserved people around him, could be scared of her boldness.
Naruto would probably feel abandoned at first. He might become more withdrawn and have trust issues. But as time goes on, he could grow stronger out of a need to prove himself. He may also form closer bonds with his friends in Konoha, like Sasuke and Sakura, as they become his new family in a way.
One possible reason could be some sort of dark influence or curse that makes her lose her maternal instincts. Maybe a powerful enemy targets her and in order to protect Naruto from further danger related to her, she feels forced to abandon him. Another reason might be that she is made to believe false information about Naruto, such as that he will bring great disaster to the village in the future.
Maybe she's been possessed. In some fanfictions, characters can be taken over by dark forces. So Kushina could be under the control of some evil entity and that's why she hurts Naruto.
It could also be due to some external influence. Perhaps an enemy used some kind of mind - control or manipulation on Kushina. They made her think that Naruto was a threat, so she decided to disown him. In the Naruto universe, there are many powerful villains who could potentially do this kind of thing.