One possible plotline could be Hermione's search for a magical cure. She could travel to different parts of the wizarding world, seeking out ancient spells or potions that might heal her. Along the way, she might face various challenges and obstacles, like dark wizards who want to stop her from finding a cure because they see her as a threat to their power.
Another plotline could revolve around how her friends deal with her illness. Harry and Ron could set out on a quest to find a way to save her. They might have to make difficult choices, like sacrificing their own safety or breaking some wizarding laws. This would show the depth of their friendship and loyalty to Hermione.
There could also be a plotline where Hermione uses her cancer as a motivation to write a book about her experiences and knowledge. This book could become a guide for other wizards and witches facing serious illnesses. It could also lead to a change in the way the wizarding world views and treats diseases, with Hermione at the forefront of this medical revolution.
One possible plotline could be Naruto struggling to keep his ninja duties while dealing with the illness. He might try to hide it from his friends at first. Another could be him seeking out rare medical ninjutsu or herbs to cure himself. Maybe he teams up with some unlikely allies in his search for a cure.
A plotline might involve Naruto's struggle to maintain his status as a ninja while dealing with the cancer. He could face discrimination from some in the village who think he's no longer fit for duty. Or there could be a plot where the Akatsuki somehow find out about his condition and try to use it to their advantage, like blackmailing him or using it as a distraction in a battle.
One interesting plotline could be that Draco and Hermione are forced to work together in a cancer research project at Hogwarts. They start off hating each other as always, but as they see the effects of cancer on patients, they gradually put aside their differences. Hermione's vast knowledge of magic and Draco's family's connections to certain potions ingredients could lead to them making a significant discovery in the fight against cancer in the wizarding world.
One plotline could be the secrecy around the baby. Since Sirius was on the run for a long time, they might have to keep the baby's existence a secret from the Ministry. Hermione would use her intelligence to create protective spells and hiding places. Another could be the baby showing extraordinary magical abilities early on, which attracts unwanted attention from dark forces.
One possible plotline could be Percy's journey of dealing with the diagnosis. He might initially be in denial, then gradually accept it and start treatments. Another could be how his friends and family react, like his friends rallying around him to keep his spirits up.
One plotline could be that they are forced to work together on a dangerous magical project. During this time, they start to see each other in a new light and fall in love, which eventually leads to having a son.
One plotline could be that Hermione is suddenly thrust into the spotlight of Muggle royalty. She has to learn all the protocols and etiquettes while still trying to keep up with her studies at Hogwarts. This causes some hilarious and also some tense situations as she tries to juggle both worlds. Another plotline might be that there is a threat to the Muggle royal family, and Hermione, with her magical skills, has to protect them. This could involve her using spells to defend against dark wizards who are after the royals for some unknown reason.
One possible plotline could be that they meet under some unusual circumstances, perhaps during a time when the wizarding world is in chaos. Lucius, who is used to a certain way of life, is initially resistant to his connection with Hermione but gradually comes to respect and care for her. Hermione, on the other hand, might see the good in Lucius beneath his cold exterior.
One possible plotline could be that Hermione discovers a hidden side of Snape during her research in the library. This could lead to a series of conversations where Snape starts to see Hermione in a different light, not just as another student. Another could be that in a dangerous situation, Hermione and Snape are forced to work together, and through this experience, they develop a newfound respect for each other.
One possible plotline could be Hermione using her intelligence to outwit her targets. For example, she might study their habits and weaknesses in the same way she studies for her Hogwarts classes. Another plotline could involve her having a moral dilemma. As an assassin, she would be taking lives, but her Gryffindor values might conflict with this. She could struggle with whether to follow orders or do what she believes is right. A third plotline could be her forming an unlikely alliance with other characters. Maybe she teams up with someone from the wizarding underworld who has skills she needs to complete her missions, and together they face various challenges and enemies.