Maybe the male OC is from a different dimension where the Omnitrix works in a completely different way. He accidentally gets transported to the Ben 10 universe. His Omnitrix has some unique alien forms that are not known in this universe. He teams up with Ben and Gwen to fight a new common enemy that is attracted to the strange energy his Omnitrix emits. Along the way, he learns about the values of friendship and courage from them.
One interesting storyline could be about Ben exploring new alien forms that were previously unknown in the official series. Maybe he discovers a form that has unique powers that he has to learn to control quickly to face a new and powerful enemy.
He could have a unique personality trait, like being extremely shy but when he transforms using the Omnitrix, he becomes super confident. For example, if he transforms into a big, strong alien, his normal timid self disappears and he becomes a fearless leader in battle.
Another could be an OC with the Omnitrix getting stuck in a parallel universe where the rules of the Omnitrix are different. For example, instead of being able to transform into known aliens, the OC has to figure out how to use new and strange alien forms that are native to that universe. This could lead to all sorts of adventures as the OC tries to find a way back home.
You could also write a fanfiction where an OC is accidentally bonded with the Omnitrix in a way that it can't be removed. The OC then has to learn to live with it and use its powers for good, but they face challenges as they are not Ben. They might have to deal with people who are suspicious of them having the Omnitrix and also face enemies who are specifically after the device because of its new and unexpected host.
One possibility is that the story could explore how Gwen's personality changes when she has the Omnitrix. She might become more confident or more responsible. Also, there could be new villains who are attracted to the Omnitrix now that Gwen has it. She would then have to face these threats and protect the Omnitrix from falling into the wrong hands.
An old enemy of the Omnitrix's creator could be a great main antagonist. Maybe this enemy was locked away for centuries and now has escaped and blames the Omnitrix for his imprisonment. He would be extremely powerful and have knowledge of the Omnitrix's weaknesses that Ben doesn't even know yet.
Develop a really unique OC. Give them a distinct personality, backstory, and motivation. For example, an OC who is an alien - human hybrid with a complex family history related to different species in the Ben 10 universe. This will make readers more interested in the character's journey with the Omnitrix.
Well, Ben is obviously one of the main characters as the story is centered around him and the Omnitrix. Gwen might also be a main character as she often plays an important role in Ben's adventures, providing support or using her own magical abilities to help out. Grandpa Max could be another main character, offering his wisdom and experience to guide Ben through various situations.
The plot could center around the OC having a unique item that attracts the attention of both Ben and Gwen. This item might be a key to an ancient power or a device that can manipulate time. As they all try to figure out what the item is and how to use it, they face challenges from other alien races who also want the item. Ben uses his various alien forms to battle these foes, Gwen uses her intelligence and magic to solve the mysteries related to the item, and the OC provides insights based on its own knowledge of the item's origin.
To create a unique male OC, consider his appearance. He could have a unique scar or birthmark that has a special meaning related to the Omnitrix. Also, think about his skills and knowledge. He might be a genius when it comes to technology because he has spent so much time trying to understand the Omnitrix. His relationships are important too. He could have a mentor figure who is an old alien that he met during one of his early transformations.