A group of poachers who target Ghost - type Pokemon could be the main antagonists. They might be after Phoebe's strong Ghost - type Pokemon for their own illegal purposes, like selling them on the black market. Another option could be a mad scientist - type character who wants to use Ghost - type Pokemon in some unethical experiments. Or perhaps a powerful, evil trainer who has a vendetta against Phoebe and her Gym, and uses his own strong Pokemon to try and defeat her and take over the Gym.
Another potential rival could be a young prodigy named Lily. She has a diverse team of Pokemon that she has trained from a very young age. Lily is very confident in her abilities and constantly tries to outdo Phoebe in battles. She might also have some unique training methods that Phoebe has to figure out in order to defeat her.
It could be Team Rocket - style villains who want to capture Naruto because they think he has some special power that can help them control Legendary Pokemon. They might try to trick him or set traps for him.
Another antagonist could be a powerful and corrupted legendary Pokemon. It could be causing chaos in the Pokemon world and Naruto would have to use his skills and the power of his Pokemon team to stop it. This would be a great challenge as legendary Pokemon are extremely powerful, but Naruto has his own set of unique abilities that could give him an edge.
Perhaps a powerful and mysterious trainer. This trainer is jealous of Ash's connection with his Pokemon and his ability to conduct these experiments. He wants to prove that he is the better trainer. So he tries to disrupt Ash's experiments by challenging him to battles at inconvenient times. He also spreads false rumors about Ash's experiments being dangerous to other Pokemon, which causes some local Pokemon communities to be hostile towards Ash.
There could be a new, mysterious force that is neither from the Naruto world nor fully part of the Olympian world. This force wants to disrupt the balance between the two worlds and sees Naruto as the key to achieving its goals. It could manipulate both sides and create chaos.
One potential antagonist could be a new and mysterious organization that is similar to Akatsuki but with different motives. They might be interested in using Daisuke to open a portal to a different dimension or something like that. They would be constantly trying to kidnap Daisuke and force him to cooperate. Also, Orochimaru or his remaining followers could be antagonists. Even though Orochimaru has changed somewhat in the series, there could still be some of his followers who are more radical and want to use Daisuke for their dark experiments, believing that he has some special chakra or ability that could help them achieve their twisted goals.
Another option could be Orochimaru. He has his own motives and is always looking for power. He could be the head of a powerful gang in the criminal underworld of the Naruto world. He would constantly be trying to capture Naruto or his friends to use them for his experiments or to gain more power over the ninja world.
The Akatsuki could still be the main antagonists. They might be interested in Naruto's tails for their own dark purposes, like using their power to create a super - weapon or gain control over the ninja world. Another option could be a secret group of rogue ninjas who have a vendetta against the Uzumaki clan and see Naruto's tails as a symbol of their power that they want to destroy.
One possible antagonist could be a jealous noble from Naruto's own kingdom who feels that Naruto doesn't deserve the prince title. This person might try to undermine Naruto at every turn, spreading false rumors about him or trying to sabotage his diplomatic efforts.
The Akatsuki could still be a major antagonist. Even if Naruto is emperor, they might oppose his rule as it goes against their own goals of chaos and obtaining the tailed beasts.