Perhaps the Nomu is sent to attack Izuku during a critical moment, like when he's on a mission to save someone. Izuku gets hurt while protecting the innocent. This incident could lead to a change in the way the other characters view Izuku. Some might see him as more vulnerable, while others are inspired by his selfless act. Izuku, on his part, has to deal with the physical pain and the new - found perception of him by his peers.
In a fanfiction, the Nomu could be controlled by a hidden villain who wants to break Izuku's spirit. So, the Nomu injures Izuku in a brutal way. This forces Izuku to re - evaluate his approach to heroism and his relationships with his friends and mentors. He may have to find new ways to heal and grow stronger, both physically and mentally.
Well, in such a fanfiction, Izuku might end up in a coma. His friends would be really worried. Ochaco might constantly visit him in the hospital, hoping he wakes up soon. And Bakugo could have a change of heart, realizing he should have been nicer to Izuku all along.
One possible storyline could be that Naruto is wrongly accused of a serious crime in the village. Everyone turns against him, even his friends. He might be shunned and face physical attacks from villagers who once feared or respected him. Naruto would then have to struggle to prove his innocence while dealing with the emotional pain of being betrayed by those he cared about.
The story could progress with Izuku's friends vowing revenge on Nomu. They might start training non - stop to become stronger and face Nomu again.
One possible storyline could be Maia getting hurt during a courtroom battle. Maybe she is physically attacked by an angry client or a witness. Another could be her being emotionally hurt when a close colleague betrays her trust. For example, they might leak some confidential information about her which causes her a great deal of distress.
He would likely feel a sense of failure. Since Izuku has such a strong drive to be a hero, being hurt by the Nomu might make him think he's not good enough yet. It could be a big blow to his self - confidence.
One possible storyline could be that in a mission gone wrong, Kurenai accidentally uses a jutsu that ends up hurting Naruto. Maybe she misjudges the situation and her genjutsu affects Naruto in an unexpected and harmful way.
Well, in some fanfics, Sakura might be jealous of Naruto's growing power and relationship with others. So she could try to undermine him, which in turn hurts Naruto. Maybe she spreads false rumors about him in the village. Another idea is that Sakura is forced to choose between Naruto and Sasuke in a dangerous situation, and her choice, even if it's not completely her fault, ends up hurting Naruto deeply. It could also be that Sakura's overzealous medical treatment, in an attempt to save Naruto from a serious injury, actually causes him more pain and harm.
One possible storyline could be that Shikadai is on a mission and gets caught in an unexpected ambush by a group of powerful enemies. He might be outnumbered and sustain injuries while trying to fight them off and protect his comrades. Another could be that he's involved in a training accident that goes horribly wrong, like a jutsu backfiring on him and causing him physical harm.
Maybe Spike tries to prove himself by joining in on a dangerous adventure with the Mane 6. They are exploring an old, abandoned castle filled with traps. Spike, being smaller and not as experienced as the others, steps on a pressure - sensitive tile that releases a volley of arrows. He gets hurt as some of the arrows graze his body, and then the group has to figure out how to treat his wounds while still making their way through the dangerous castle.
One possible storyline could be that Brennan is injured during an excavation. Maybe a cave - in occurs and she gets trapped under some rubble. Her team then has to race against time to save her while she struggles with her injuries. Another could be that she is attacked while working late at the Jeffersonian. This would not only lead to her physical hurt but also psychological trauma as she tries to figure out who did it and why.