Which anime based on depression manga is most impactful?

Well, characters like One Punch Man have really engaging storylines. His unique power and the challenges he faces make it quite interesting.

Characters like Goku from Dragon Ball and Naruto from Naruto have very impactful storylines. Their growth and challenges keep fans engaged.

For me, 'Clannad' stands out. It combines elements of family, friendship, and love, creating a deeply emotional and impactful narrative. The character development is amazing and makes you really care about them.

For me, 'Death Note' has a memorable and impactful ending. It's full of twists and turns that keep you on the edge of your seat until the very end. The way it concludes really makes you think about the themes and characters.

One of the most popular anime comedies based on manga is 'Gekkan Shoujo Nozaki-kun'. It has a great fan base due to its hilarious characters and funny storylines.

It's hard to say for sure, but 'Cardcaptor Sakura' is up there. It's known for its charming magic and heartwarming moments that resonate with viewers of all ages.

That's hard to say. Different people have different preferences. But 'That Time I Got Reincarnated as a Slime' seems to be quite popular.

Doraemon is a good option. The characters are cute, and it teaches valuable lessons in an entertaining way. Also, the adventures are exciting for kids to follow.

For me, the death of Uvogin was quite memorable. It showed the harshness and danger of the world in Hunter x Hunter. It also had consequences for the other characters' actions and decisions.

I'd say Death Note. The anime is renowned for its close alignment with the manga. It replicates the intricate plot and suspenseful moments with remarkable accuracy. Minor additions or alterations are made to enhance the visual and auditory aspects, but they don't stray far from the original manga's framework.