It could be that they heard a sound or saw something unusual in that direction. Or perhaps it's part of the story's plot to have them look over there for a specific reason.
The cartoon character might look over there because they're following someone or something, or they could be responding to a cue or signal. It's hard to say for sure without more context.
Maybe there's something interesting or important that caught their attention.
Maybe it's looking out for something or someone. Could be curious or cautious.
Maybe they're being cautious or checking for something behind them.
Maybe it's curious about what's on the other side. Noses can be quite nosy sometimes!
Maybe it's a characteristic pose or expression to show a certain emotion or attitude.
It could be that the cartoon character lost something important or is in a hurry to reach a goal before time runs out. That would explain the frantic look.
Maybe it saw something unexpected or shocking.
The cartoon character might be worried because it's lost or about to encounter something scary. Or perhaps it's worried about a friend or family member.
Maybe it had a bad day or something didn't go its way.
The reason could be that the story's plot has taken an unexpected turn, leaving the character unsure of what to do or how to react, resulting in that confused look.
Maybe they got some kind of virus or had an accident in the story.